D-2Health

Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)

Agency: Department of Health and Human Services
Run by: National Institutes of Health
Target applicants: Special district governments, Native American tribal governments (Federally recognized), City or township governments, For profit organizations other than small businesses, County governments, Small businesses, Native American tribal organizations (other than Federally recognized tribal governments), Independent school districts, State governments, Public housing authorities/Indian housing authorities, Public and State controlled institutions of higher education, Others (see text field entitled "Additional Information on Eligibility" for clarification), Nonprofits that do not have a 501(c)(3)
Application period: 2024-11-21 ~ 2026-11-17
Contact: National Institutes of Health 301-402-2541

Open in EDIT and start the application View on Grants.gov Application site

Source: Grants.gov

How to apply

Register your organization on SAM.gov to get a UEI (Unique Entity ID). It can take up to 10 business days to become active, and it must be renewed every year. SAM.gov
Create a Grants.gov account and add an applicant profile with your UEI. The E-Business Point of Contact named in SAM.gov gives the person who submits the AOR role. Grants.gov
On the opportunity page, select Apply to create a Workspace. Complete the SF-424 and the other required forms in Workspace. Opportunity page
Attach the narrative documents the NOFO asks for (such as the Project Narrative, Project Abstract and Budget Justification) in Workspace. EDIT can draft them from your materials. Workspace
Submit from Workspace, then check the status with your Grants.gov tracking number. Track my application

Overview

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducted clinical trials to assess the efficacy or effectiveness of complementary and integrative health interventions in NCCIH- designated areas of high research priority. Applications submitted under this NOFO are expected to propose a remotely delivered and conducted fully powered clinical trial with no in-person contact between research staff and study participants and may utilize mHealth tools or technologies. Applicants must provide justification for the remotely delivered approach and provide preliminary data on the feasibility and safety of the approach, along with evidence that the intervention has promise of clinical benefit. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NOFO. Opportunity number: PAR-25-268 Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.